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State Level Eligibility Test

SLET: Life Sciences

Code No. : 04
Subject : LIFE SCIENCES
PAPER III

21. Structure, classification, genetics, reproduction and physiology of bacteria and viruses (of
bacteria, plants and animals); Mycoplasma protozoa and yeast (general accounts).

22. Microbial fermentation; Antibiotics, organic acids and vitamins; Microbes in decomposition and recycling processes; Symbiotic and asymbiotic N2-fixation; Microbiology of water, air, soil and sewage: Microbes as pathological agents in plants, animals and man; General design and applications of a biorermenter Biofertilizer.

23. Antigen; Structure and functions of different clauses of immunoglobulins; Primary and secondary immune response; Lymphocytes and accessory cells; Humoral and cell mediated immunity; MHC; Mechanism of immune response and generation of immunological diversity; Genetic control of immune response, Effector mechanisms; Application of immunological techniques.

24. Enzyme kinetics (negative and positive cooperativity); Regulation of enzymatic activity; Active sites; Coenzymes: Activators and inhibitors, isoenzymes, allosteric enzymes; Ribozyme and abzyme.

25. Van der Waal’s, electrostatic, hydrogen bonding and hydrophobic Interactions; Primary structure of proteins and nucleic acids; Conformation of proteins and polypeptides (secondary, tertiary, quaternary and domain structure); Reverse turns and Ramachandran plot; Structural polymorphism of DNA, RNA and three dimensional structure of tRNA; Structure of carboyhydrates, polysaccharides, glycoproteins and peptido-glycans; Helix-coil transition; Energy terms in biopolymer conformational calculation.

26. Glycolysis and TCA cycle; Glycogen breakdown and synthesis; Gluconeogenesis; Interconversion of hexoses and pentoses; Amino acid metabolism; Coordinated control of metabolism; Biosynthesis of purines and pyrimidines; Oxidation of lipids; Biosynthesis of fatty acids; Triglycerides; Phospholipids; Sterols.